Decreased expression of Cdc25a in breast stroma of diethylstilbestrol treated female ACI rats
نویسندگان
چکیده
منابع مشابه
Interaction of dimethylbenzanthracene and diethylstilbestrol on mammary adenocarcinoma formation in female ACI rats.
It has been reported that X-irradiation and diethylstilbestrol (DES) act synergistically on mammary adenocarcinoma formation in female ACI rats. The physical carcinogen, X-irratiation, was replaced by a chemical carcinogen, dimethylbenzanthracene (DMBA), and their interaction was studied in this system. Thirty-three female ACI rats were given 13.3 mg of DMBA per 100 grams of body weight. A tota...
متن کاملEffect of interval between neutron radiation and diethylstilbestrol on mammary carcinogenesis in female ACI rats.
Both radiation and diethylstilbestrol (DES) are carcinogens for the mammary gland of ACI female rats. When DES is given at about the same time as radiation, DES and radiation interact in a synergistic fashion particularly in regard to the number of mammary adenocarcinomas per rat. We have studied the effect of increasing the time interval between radiation and DES on the capacity of DES to enha...
متن کاملSynergistic interactions of various doses of diethylstilbestrol and x-irradiation on mammary neoplasia in female ACI rats.
The intent of this study was to investigate the relationship between diethylstilbestrol (DES) dose and its synergistic inter action with X-irradiation for mammary carcinogenesis in ACI rats. In addition, the role of prolactin in this synergism was studied. Ten groups of approximately 25 female ACI rats, 84 to 91 days of age, were implanted s.c. with a compressed 20mg pellet containing either 5,...
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15 صفحه اولInteraction of Dimethylbenzanthracene and Diethylstilbestrol on Mammary Adenocarcinoma Formation in Female ACI Rats1
It has been reported that X-irradià tion and diethylstilbestrol (DES) act synergistically on mammary adenocarcinoma for mation in female ACI rats. The physical carcinogen, X-irradia tion, was replaced by a chemical carcinogen, dimethylbenzan thracene (DMBA), and their interaction was studied in this system. Thirty-three female ACI rats were given 13.3 mg of DMBA per 100 grams of body weight. A ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.lb497